Thursday, 21 April 2011

Malignant Peritoneal Mesothelioma


Malignant peritoneal mesothelioma (MPM) is a rare and aggressive tumor of the peritoneum (the tissue that surrounds the abdomen) and is considered a universally fatal disease. Of all types of mesothelioma, only 20% to 33% arise from the peritoneum itself.  Most mesotheliomas commonly originate in the pleura. When the peritoneal cancer spreads, doctors call it diffuse peritoneal mesothelioma. Peritoneal mesothelioma starts when an individual breathes in asbestosfibers, usually as part of their job. Asbestos is a natural mineral that is resistant to heat, fire, and electricity. Until the late 1970s, asbestos was widely used in the automotive, building, fireproofing, roofing, and shipbuilding industries. Adhesives, ceiling tiles, floor tiles, paint, and numerous plastics contained asbestos. Easily released into the air, asbestos fibers are very small, which makes it very easy for workers to breathe them into their lungs. Today’s industries no longer use asbestos.

The asbestos fibers get into the body and move to the digestive system, slicing through the stomach and intestines. In peritoneal mesothelioma, the asbestos fibers puncture the abdominal lining, which is responsible for secreting lubrication for the organs to process food. When this happens, a cancerous growth forms in the abdominal lining. The incubation period for mesothelioma can be up to fifty years, with symptoms remaining dormant after exposure to asbestos. By the time symptoms appear, the peritoneal mesothelioma has usually already progressed and spread throughout the body. Adding difficulty in detecting peritoneal mesothelioma is the fact that its symptoms are common and mimic other conditions (some of which are minor conditions), and with such a long incubation period after exposure, a physician may treat a patient for the wrong illness, such as indigestion or heartburn.

Individuals with malignant peritoneal mesothelioma typically have symptoms such as swelling in the abdominal area, sudden loss of weight and appetite, nausea, constipation, and pain in the abdominal region. Other common symptoms of peritoneal mesothelioma include abdominal lumps, anemia, blood clots, chest pain, coughing, difficulty breathing, difficulty swallowing, fever, fluid retention in the abdominal cavity, constipation, hernia, nausea, and obstructions of the bowel. Because these symptoms mimic other conditions and are not specific to peritoneal mesothelioma, sometimes malignant peritoneal mesothelioma is not diagnosed, especially if the patient has no idea or does not recall being exposed to asbestos.

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